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Ionis Pharmaceuticals (IONS): analyst forecast and price target

$42.94 −2.67% close 16.10.26 · market cap $7.0B · Healthcare · Biotechnology
Price targets and ratings of

Analyst consensus

Strong Buy

13 Buy3 Hold0 Sell

Ratings of 16 analysts in the last 3 months · top analysts only

12-month forecast

$82.33+91.7% upside

Based on 16 price targets given in the last 3 months, the average target is $82.33, the highest $100, the lowest $54.00. The average is +91.7% from the last price of $42.94.

$40.00$60.00$80.00$100Jan 26AprJulOctJan 27AprJulOctHigh$100Average$82.33Low$54.00
Highest target $100 Average target $82.33 Lowest target $54.00
AnalystFirmPrice target RatingUpsideAction Date Move vs SPY
Joon Lee★★★★★★★★★★#73 · hits 58% · avg +36.3% Truist Financial $46.00 → $88.00+91.3% Buy +104.9% Upgrade 14.10.26on TipRanks 19:50 +3.0%next day −1.6%
Jason Gerberry★★★★★★★★★★#184 · hits 63% · avg +21.5% Bank of America Securities $91.00 Buy +111.9% Reiterated 09.10.26on TipRanks 06:21 +4.0%next day −3.5% · 5 days −3.2%
Mitchell Kapoor★★★★★★★★★★#1086 · hits 45% · avg +12.2% H.C. Wainwright $100 Buy +132.9% Reiterated 08.10.26on TipRanks Oct 9 09:15 −1.5%next day +4.0% · 5 days +2.2%
Luca Issi★★★★★★★★★★#11187 · hits 39% · avg −2.1% RBC Capital $85.00 Buy +98.0% Reiterated 08.10.26on TipRanks 21:45 +4.0%next day −3.5% · 5 days −3.2%
Justin Kim★★★★★★★★★★#1624 · hits 50% · avg +13.9% Oppenheimer $85.00 Buy +98.0% Reiterated 24.09.26on TipRanks 08:10 −0.2%next day +1.0% · 5 days +0.8%
Gary Nachman★★★★★★★★★★#7384 · hits 47% · avg +0.3% Canaccord Genuity $85.00 Buy +98.0% Reiterated 24.09.26on TipRanks Sep 23 07:15 −3.3%next day −0.2% · 5 days +2.3%
Mitchell Kapoor★★★★★★★★★★#1086 · hits 45% · avg +12.2% H.C. Wainwright $100 Buy +132.9% Reiterated 24.09.26on TipRanks Sep 23 06:26 −3.3%next day −0.2% · 5 days +2.3%
David Lebowitz★★★★★★★★★★#597 · hits 60% · avg +14.2% Citi $54.00 Hold +25.8% Reiterated 23.09.26on TipRanks Sep 24 08:55 −3.3%next day −0.2% · 5 days +2.3%
Yaron Werber★★★★★★★★★★#117 · hits 59% · avg +28.0% TD Cowen $84.00 Buy +95.6% Reiterated 23.09.26on TipRanks 14:30 −3.3%next day −0.2% · 5 days +2.3%
Joseph Stringer★★★★★★★★★★#293 · hits 48% · avg +24.7% Needham $86.00 Buy +100.3% Reiterated 23.09.26on TipRanks 12:35 −3.3%next day −0.2% · 5 days +2.3%
Myles Minter★★★★★★★★★★#92 · hits 61% · avg +34.9% William Blair — Buy — Reiterated 22.09.26on TipRanks 16:07 −3.3%next day −0.2% · 5 days +2.3%
Jessica Fye★★★★★★★★★★#1182 · hits 56% · avg +9.4% J.P. Morgan $70.00 Buy +63.0% Assigned 22.09.26on TipRanks 07:00 +1.9%next day −3.3% · 5 days +1.5%
Eliana Merle★★★★★★★★★★#4163 · hits 45% · avg +3.0% Barclays $85.00 Buy +98.0% Reiterated 18.09.26on TipRanks 05:20 −5.1%next day −0.5% · 5 days −1.1%
Debjit Chattopadhyay★★★★★★★★★★#506 · hits 48% · avg +17.0% Guggenheim $89.00 → $80.00−10.1% Buy +86.3% Reiterated 14.09.26on TipRanks Sep 15 07:35 −4.7%next day −7.7% · 5 days −14.6%
Salveen Richter★★★★★★★★★★#967 · hits 51% · avg +12.5% Goldman Sachs $69.00 → $56.00−18.8% Hold +30.4% Reiterated 14.09.26on TipRanks 07:35 −4.7%next day −7.7% · 5 days −14.6%
Michael Ulz★★★★★★★★★★#6183 · hits 43% · avg +0.9% Morgan Stanley $104 Buy +142.2% Assigned 09.09.26on TipRanks Sep 8 07:55 −1.8%next day −0.8% · 5 days −15.6%
Jason Gerberry★★★★★★★★★★#184 · hits 63% · avg +21.5% Bank of America Securities $93.00 → $91.00−2.2% Buy +111.9% Reiterated 08.09.26on TipRanks 22:30 −0.8%next day −0.1% · 5 days −18.9%
Tiago Fauth★★★★★★★★★★#1228 · hits 49% · avg +13.1% Raymond James $87.00 → $84.00−3.4% Buy +95.6% Reiterated 08.09.26on TipRanks 13:10 −1.8%next day −0.8% · 5 days −15.6%
Eric Joseph★★★★★★★★★★#1258 · hits 52% · avg +11.4% Citi $100 Buy +132.9% Reiterated 04.09.26on TipRanks Sep 7 10:15 +0.3%next day −1.8% · 5 days −10.2%
Allison Bratzel★★★★★★★★★★#171 · hits 64% · avg +41.9% Piper Sandler $94.00 Buy +118.9% Reiterated 17.08.26on TipRanks 07:38 +2.9%next day +2.4% · 5 days +7.0%
Yanan Zhu★★★★★★★★★★#1136 · hits 36% · avg +15.3% Wells Fargo $95.00 Buy +121.2% Reiterated 14.08.26on TipRanks 12:55 +2.6%next day +2.9% · 5 days +5.7%
Paul Matteis★★★★★★★★★★#473 · hits 53% · avg +17.6% Stifel Nicolaus $86.00 → $68.00−20.9% Hold +58.4% Reiterated 02.08.26on TipRanks 12:51 +3.8%next day −0.7% · 5 days +2.5%
Andy Chen★★★★★★★★★★#959 · hits 67% · avg +28.8% Wolfe Research — Hold — Downgrade 15.07.26on TipRanks 17:20 +0.4%next day +0.5% · 5 days +3.9%
Akash Tewari★★★★★★★★★★#649 · hits 57% · avg +13.5% Jefferies $90.00 Buy +109.6% Reiterated 15.07.26on TipRanks 09:56 −0.8%next day +0.4% · 5 days −0.3%
William Pickering★★★★★★★★★★#5908 · hits 58% · avg +1.8% Bernstein $65.00 → $89.00+36.9% Hold +107.3% Reiterated 13.01.26on TipRanks Jan 14 02:16 −2.5%next day −0.3% · 5 days +1.2%
Mani Foroohar★★★★★★★★★★#11266 · hits 43% · avg −2.1% Leerink Partners $85.00 → $100+17.6% Buy +132.9% Reiterated 15.12.25on TipRanks 09:30 −1.2%next day −1.5% · 5 days +1.1%

Every rating the collector has kept for the last 12 months, including the earlier ones of the same analyst. Latest of each analyst

Best analysts covering Ionis Pharmaceuticals

TipRanks picks them by their record on this stock; the figures under the name are their record across all their ratings.

Most accurate

3 months Mitchell Kapoor★★★★★★★★★★H.C. Wainwright · #1086
Hits 45%215 of 481 Average return +12.2%
1 year Gary Nachman★★★★★★★★★★Canaccord Genuity · #7384
Hits 47%188 of 401 Average return +0.3%
2 years Yanan Zhu★★★★★★★★★★Wells Fargo · #1136
Hits 36%112 of 309 Average return +15.3%

Most profitable

3 months Mitchell Kapoor★★★★★★★★★★H.C. Wainwright · #1086
Hits 45%215 of 481 Average return +12.2%
1 year Gary Nachman★★★★★★★★★★Canaccord Genuity · #7384
Hits 47%188 of 401 Average return +0.3%
2 years Yanan Zhu★★★★★★★★★★Wells Fargo · #1136
Hits 36%112 of 309 Average return +15.3%

How the average price target moved

The average target of all analysts (their ratings of the 3 months before) on each day, the top analysts’ dashed, against the price; the site keeps this record since 1 October 2026. On 08.10.26: target $84.00 at a price of $44.16 (+90.2%); now: $83.89 at $42.94 (+95.4%).

$40.00$60.00$80.00Sep 15Oct 1Oct 15Top analysts$82.33Average target$83.89Price$42.94

PriceAverage targetTop analysts’ target

Recommendation trend · top analysts

020406010347Oct 255334Nov1261Dec120Jan 26212Feb5203Mar8234Apr10212May9252Jun21215Jul25209Aug331713Sep2199Oct

Strong BuyBuyHoldSell

Rating05.2606.2607.2608.2609.2610.26
Strong Buy10921253321
Buy21252120179
Hold2259139
Sell000000

Earnings and sales forecast

Next report: 04.11.26 (Q3 2026, date not confirmed)

Earnings per share

Next quarter’s EPS estimate — $-1.21 (from $-1.42 to $-0.96). Last quarter: $-0.69.

Sales

Next quarter’s sales estimate — $183M (from $160M to $225M). Last quarter: $268M.

Best top-analyst consensus in the sector · Healthcare

AXGNAxoGen
MDWDMediwound
OCULOcular Therapeutix
OVIDOvid Therapeutics
ZYMEZymeworks
About Ionis Pharmaceuticals
  • CEO: Brett Monia
  • Employees: 1,480
  • 2855 Gazelle Court, Carlsbad, CA, 92010, US
  • www.ionis.com

Founded in 1989 and headquartered in Carlsbad, California, Ionis Pharmaceuticals, Inc. is a biopharmaceutical company specializing in the discovery and development of RNA-targeted therapies within the United States. Its commercial portfolio includes three key medications: SPINRAZA, prescribed for spinal muscular atrophy (SMA) in both children and adults; TEGSEDI, an injectable treatment targeting polyneuropathy associated with hereditary transthyretin-mediated amyloidosis in adult patients; and WAYLIVRA, which addresses familial chylomicronemia syndrome and familial partial lipodystrophy. Ionis also maintains a robust pipeline, with several drug candidates currently in Phase 3 clinical trials. These include Eplontersen, a monthly self-administered subcutaneous injection designed for all forms of TTR amyloidosis; Olezarsen, intended for individuals with severe hypertriglyceridemia (SHTG); Donidalorsen, for patients suffering from hereditary angioedema; ION363, aimed at amyotrophic lateral sclerosis (ALS); Pelacarsen, developed for those with established cardiovascular disease and elevated lipoprotein(a); and Tofersen, which works by inhibiting the production of superoxide dismutase 1. Beyond these late-stage assets, the company is actively researching treatments for metabolic, infectious, renal, and ophthalmic diseases, as well as various types of cancer. The firm engages in significant collaborations, notably a strategic partnership with Biogen Inc. Additionally, it holds licensing and collaboration agreements with AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis AG, Roche, Janssen Biotech, Inc., and Flamingo Therapeutics, Inc.

Data from the stock’s TipRanks forecast page, read 5 min ago. It is read again as soon as a new rating appears and at least every 8 hours. TipRanks ↗